WebHSD17B13 (Hydroxysteroid 17 Beta Dehydrogenase 13) is a Protein Coding gene. Diseases associated with HSD17B13 include5 Alpha Reductase DeficiencyandMucopolysaccharidosis Iii. Among its related pathways areMetabolismandLipoprotein metabolism. Gene Ontology (GO) annotations related to this gene includeoxidoreductase activity. WebSep 29, 2024 · This is a single center, open-label Phase I study to assess knockdown of hepatic HSD17B13 mRNA pharmacokinetics (PK), safety, and tolerability following multiple doses of AZD7503 in male and/or female participants of non-childbearing status with NAFLD or NASH. ... U.S. Department of Health and Human Services ...
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WebJun 7, 2024 · HSD17B13 is a lipid-droplet associated protein of the 17b-hydroxysteroid dehydrogenase (HSD) family of oxidoreductases. Through our latest opn2EXPERTS call, we invite you to propose ideas for exploring the role of HSD17B13 beyond hepatocytes in the context of human diseases. WebHSD17B13. General description of the gene and the encoded protein (s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas … all in ball clemson
Characterization of essential domains in HSD17B13 for
Web17-b hydroxysteroid dehydrogenase 13 (HSD17B13) belongs to a 15-member family that is involved in various metabolic processes, including steroid hormones, fatty ac-ids, cholesterol, and bile acids (1). The human HSD17B13 gene is located on chromosome 4 (4q22.1), and its expres-sion is highly restricted to the liver, specifically in hepato- WebInformed consent was obtained from each patient. The study was approved by the Protection of Human Subjects Committee of Nanfang Hospital (approval no. NFEC-202401-K4). We obeyed the principles of the 1983 Declaration of Helsinki. ... which is associated with liver injury progression. 38 Lu et al found that HSD17B13 was a tumor suppressive … WebMar 22, 2024 · Recombinant human HSD17B13 protein was pu-rified from Escherichia coli transformed with plas-mid DNA harboring transcript A or HSD17B13 transcript D. Enzymatic activity was determined allinbet scommesse sportive